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Terbinafine is an antifungal medication used to treat pityriasis versicolor, fungal nail infections, and ringworm including jock itch and athlete's foot. [1][2][3] It is either taken by mouth or applied to the skin as a cream or ointment. [1][4] The cream and ointment should not be used for fungal nail infections. [5]
The side effects of oral treatment are significant and people without an infection should not take these drugs. [36] Azoles are the group of antifungals which act on the cell membrane of fungi. They inhibit the enzyme 14-alpha-sterol demethylase, a microsomal CYP, which is required for the biosynthesis of ergosterol for the cytoplasmic membrane.
Fluconazole is an antifungal medication used for a number of fungal infections. [5] This includes candidiasis, blastomycosis, coccidioidomycosis, cryptococcosis, histoplasmosis, dermatophytosis, and tinea versicolor. [5] It is also used to prevent candidiasis in those who are at high risk such as following organ transplantation, low birth ...
Caspofungin (INN; [1] [4] brand name Cancidas) is a lipopeptide antifungal drug from Merck & Co., Inc.. [5] It is a member of a class of antifungals termed the echinocandins. [medical citation needed] It works by inhibiting the enzyme (1→3)-β-D-glucan synthase and thereby disturbing the integrity of the fungal cell wall.
In late 2022, the WHO published its first-ever list of fungal priority pathogens — 19 fungi the agency said pose a significant threat to human health. It includes the highly drug-resistant yeast ...
References. Topical antifungal. Topical antifungaldrugs are used to treat fungal infections on the skin, scalp, nails, vagina or inside the mouth. These medications come as creams, gels, lotions, ointments, powders, shampoos, tinctures and sprays. Most antifungal drugs induce fungal cell death by destroying the cell wall of the fungus.
Echinocandins are a class of antifungal drugs [ 1 ] that inhibit the synthesis of β-glucan in the fungal cell wall via noncompetitive inhibition of the enzyme 1,3-β glucan synthase. [ 2 ][ 3 ] The class has been dubbed the " penicillin of antifungals," [ 4 ] along with the related papulacandins, as their mechanism of action resembles that of ...
Itraconazole. Itraconazole, sometimes abbreviated ITZ, is an antifungal medication used to treat a number of fungal infections. [7] This includes aspergillosis, blastomycosis, coccidioidomycosis, histoplasmosis, and paracoccidioidomycosis. [7] It may be given by mouth or intravenously.
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