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The Biopharmaceutics Classification System (BCS) is a system to differentiate drugs on the basis of their solubility and permeability. [1] This system restricts the prediction using the parameters solubility and intestinal permeability. The solubility classification is based on a United States Pharmacopoeia (USP) aperture.
Bioconcentration. In aquatic toxicology, bioconcentration is the accumulation of a water-borne chemical substance in an organism exposed to the water. [ 1][ 2] There are several ways in which to measure and assess bioaccumulation and bioconcentration. These include: octanol-water partition coefficients (K OW ), bioconcentration factors (BCF ...
A Rotary Vacuum Filter Drum consists of a cylindrical filter membrane that is partly sub-merged in a slurry to be filtered. The inside of the drum is held lower than the ambient pressure. As the drum rotates through the slurry, the liquid is sucked through the membrane, leaving solids to cake on the membrane surface while the drum is submerged.
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The Variant Call Format or VCF is a standard text file format used in bioinformatics for storing gene sequence variations. The format was developed in 2010 for the 1000 Genomes Project and has since been used by other large-scale genotyping and DNA sequencing projects. [ 1][ 2] VCF is a common output format for variant calling programs due to ...
In bioinformatics, neighbor joining is a bottom-up (agglomerative) clustering method for the creation of phylogenetic trees, created by Naruya Saitou and Masatoshi Nei in 1987. [1] Usually based on DNA or protein sequence data, the algorithm requires knowledge of the distance between each pair of taxa (e.g., species or sequences) to create the ...
Survival function. The survival function is a function that gives the probability that a patient, device, or other object of interest will survive past a certain time. [ 1] The survival function is also known as the survivor function[ 2] or reliability function. [ 3] The term reliability function is common in engineering while the term survival ...
A fillet knife (also called a filleting knife) is a kitchen knife used for filleting. It gives good control and aids in filleting. It is a very flexible member of the boning knife family that is used to filet and prepare fish. Fillet knife blades are typically 15 to 28 cm (6 to 11 in) long. This allows them to move easily along the backbone and ...
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