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An opioid overdose is toxicity due to excessive consumption of opioids, such as morphine, codeine, heroin, fentanyl, tramadol, and methadone. [3][5] This preventable pathology can be fatal if it leads to respiratory depression, a lethal condition that can cause hypoxia from slow and shallow breathing. [3] Other symptoms include small pupils ...
tolerance – the diminishing effect of a drug resulting from repeated administration at a given dose. v. t. e. Physical dependence is a physical condition caused by chronic use of a tolerance -forming drug, in which abrupt or gradual drug withdrawal causes unpleasant physical symptoms. [4][5] Physical dependence can develop from low-dose ...
Tricyclics have a narrow therapeutic index, i.e., the therapeutic dose is close to the toxic dose. [7] Factors that increase the risk of toxicity include advancing age, cardiac status, and concomitant use of other drugs. [8] However, serum drug levels are not useful for evaluating risk of arrhythmia or seizure in tricyclic overdose. [9]
Community members waved signs that read “Save City Drug,” “Targeting small pharm” and “Hospice patients need City Drug!” as the board members left the room. Cheyenne community members
A drug overdose (overdose or OD) is the ingestion or application of a drug or other substance in quantities much greater than are recommended. [2][3] Typically it is used for cases when a risk to health will potentially result. [2] An overdose may result in a toxic state or death. [3]
Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...
1,106,000 US residents (1968–2020) [4] A person using an inhalant. Substance abuse, also known as drug abuse, is the use of a drug in amounts or by methods that are harmful to the individual or others. It is a form of substance-related disorder. Differing definitions of drug abuse are used in public health, medical, and criminal justice contexts.
e. Benzodiazepine withdrawal syndrome (BZD withdrawal) is the cluster of signs and symptoms that may emerge when a person who has been taking benzodiazepines as prescribed develops a physical dependence on them and then reduces the dose or stops taking them without a safe taper schedule.