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  2. Promoter (genetics) - Wikipedia

    en.wikipedia.org/wiki/Promoter_(genetics)

    The repressor will then bind to the operator, stopping the manufacture of lactase. In genetics, a promoter is a sequence of DNA to which proteins bind to initiate transcription of a single RNA transcript from the DNA downstream of the promoter. The RNA transcript may encode a protein (mRNA), or can have a function in and of itself, such as tRNA ...

  3. Regulatory sequence - Wikipedia

    en.wikipedia.org/wiki/Regulatory_sequence

    Regulatory sequence. A regulatory sequence is a segment of a nucleic acid molecule which is capable of increasing or decreasing the expression of specific genes within an organism. Regulation of gene expression is an essential feature of all living organisms and viruses.

  4. 5′ flanking region - Wikipedia

    en.wikipedia.org/wiki/5′_flanking_region

    The 5′ flanking region is a region of DNA that is adjacent to the 5′ end of the gene. The 5′ flanking region contains the promoter, and may contain enhancers or other protein binding sites. It is the region of DNA that is not transcribed into RNA. Not to be confused with the 5′ untranslated region, this region is not transcribed into ...

  5. Enhancer (genetics) - Wikipedia

    en.wikipedia.org/wiki/Enhancer_(genetics)

    In genetics, an enhancer is a short (50–1500 bp) region of DNA that can be bound by proteins (activators) to increase the likelihood that transcription of a particular gene will occur. [1][2] These proteins are usually referred to as transcription factors. Enhancers are cis -acting.

  6. Promoter activity - Wikipedia

    en.wikipedia.org/wiki/Promoter_activity

    Promoter activity. Promoter activity is a term that encompasses several meanings around the process of gene expression from regulatory sequences — promoters [2] and enhancers. [3] Gene expression has been commonly characterized as a measure of how much, how fast, when and where this process happens. [4] Promoters and enhancers are required ...

  7. Gene regulatory network - Wikipedia

    en.wikipedia.org/wiki/Gene_regulatory_network

    A gene (or genetic) regulatory network (GRN) is a collection of molecular regulators that interact with each other and with other substances in the cell to govern the gene expression levels of mRNA and proteins which, in turn, determine the function of the cell. GRN also play a central role in morphogenesis, the creation of body structures ...

  8. Expression vector - Wikipedia

    en.wikipedia.org/wiki/Expression_vector

    Expression vectors are the basic tools in biotechnology for the production of proteins. The vector is engineered to contain regulatory sequences that act as enhancer and promoter regions and lead to efficient transcription of the gene carried on the expression vector. [1] The goal of a well-designed expression vector is the efficient production ...

  9. Intergenic region - Wikipedia

    en.wikipedia.org/wiki/Intergenic_region

    Intergenic regions may contain a number of functional DNA sequences such as promoters and regulatory elements, enhancers, spacers, and (in eukaryotes) centromeres. [2] They may also contain origins of replication, scaffold attachment regions, and transposons and viruses.