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Hepatitis C was finally "discovered" in 2005 when a Japanese team was able to propagate a molecular clone in a cell culture called Huh7. [139] This discovery enabled proper characterization of the viral particle and rapid research into the development of protease inhibitors replacing early interferon treatments.
The hepatitis C virus belongs to the genus Hepacivirus, a member of the family Flaviviridae. Before 2011, it was considered to be the only member of this genus. However a member of this genus has been discovered in dogs: canine hepacivirus. [6] There is also at least one virus in this genus that infects horses. [7]
Nobel Prize for Medicine (2020) Scientific career. Fields. Virology. Harvey James Alter (born September 12, 1935) is an American medical researcher, virologist, physician and Nobel Prize laureate, who is best known for his work that led to the discovery of the hepatitis C virus. [1] Alter is the former chief of the infectious disease section ...
“Hepatitis C is a blood-borne virus,” says Dr. Dieterich. “It is transmitted through the blood, so IV drug use is a major driver of the virus, especially now due to the heroin epidemic.
Sir Michael Houghton (born 1949) is a British scientist and Nobel Prize laureate. Along with Qui-Lim Choo, George Kuo and Daniel W. Bradley, he co-discovered Hepatitis C in 1989. [2] He also co-discovered the Hepatitis D genome in 1986. [3] The discovery of the Hepatitis C virus (HCV) led to the rapid development of diagnostic reagents to ...
Hepatitis C vaccine. A hepatitis C vaccine, a vaccine capable of protecting against the hepatitis C virus (HCV), is not yet available. Although vaccines exist for hepatitis A and hepatitis B, development of an HCV vaccine has presented challenges. [1] No vaccine is currently available, but several vaccines are currently under development. [2][3]
Chronic hepatitis C progresses towards cirrhosis, with estimates of cirrhosis prevalence of 16% at 20 years after infection. [125] While the major causes of mortality in hepatitis C is end stage liver disease, hepatocellular carcinoma is an important additional long term complication and cause of death in chronic hepatitis.
In 1989 Michael Houghton's team at Chiron Corporation discovered hepatitis C. [71] New viruses and strains of viruses were discovered in every decade of the second half of the 20th century. These discoveries have continued in the 21st century as new viral diseases such as SARS [72] and nipah virus [73] have emerged. Despite scientists ...
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