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2. List of opioids - Wikipedia

   en.wikipedia.org/wiki/List_of_opioids

   Carbonate derivatives of 14β-hydroxycodeine "viz., 14β-hydroxy-6-O-(methoxycarbonyl)codeine, 6-O-methoxycarbonyl-14β-(methoxycarbonyloxy)codeine, and 14β-acetoxy-6-O-methoxy-carbonylcodeine, potential substrates for ring C modification in morphinane (sic) alkaloids, were synthesized for the first time."

3. List of Schedule II controlled substances (U.S.) - Wikipedia

   en.wikipedia.org/wiki/List_of_Schedule_II...

   This is the list of Schedule II controlled substances in the United States as defined by the Controlled Substances Act. [ 1] The following findings are required for substances to be placed in this schedule: [ 2] The drug or other substance has a high potential for abuse. The drug or other substance has a currently accepted medical use in ...

4. Opioid use disorder - Wikipedia

   en.wikipedia.org/wiki/Opioid_use_disorder

   Opioid use disorder ( OUD) is a substance use disorder characterized by cravings for opioids, continued use despite physical and/or psychological deterioration, increased tolerance with use, and withdrawal symptoms after discontinuing opioids. [ 12] Opioid withdrawal symptoms include nausea, muscle aches, diarrhea, trouble sleeping, agitation ...

5. Pain management - Wikipedia

   en.wikipedia.org/wiki/Pain_management

   Pain management is an aspect of medicine and health care involving relief of pain ( pain relief, analgesia, pain control) in various dimensions, from acute and simple to chronic and challenging. Most physicians and other health professionals provide some pain control in the normal course of their practice, and for the more complex instances of ...

6. Oxycodone - Wikipedia

   en.wikipedia.org/wiki/Oxycodone

   Side effects. Main side effects of oxycodone [ 43] Two tablets (10 mg) of oxycodone and safety blisters. Most common side effects of oxycodone include reduced sensitivity to pain, delayed gastric emptying, euphoria, anxiolysis (a reduction in anxiety), feelings of relaxation, and respiratory depression. [ 44]

7. Timeline of the opioid epidemic - Wikipedia

   en.wikipedia.org/wiki/Timeline_of_the_opioid...

   1911 - 1990s According to the FDA's Timeline of Selected FDA Activities and Significant Events Addressing Opioid Misuse and Abuse, before the 1990s, most opioid pain medications were used to manage pain that was either acute or related to cancer. The FDA said that there was an increase in the use of opioids because physicians were not treating ...