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Multiple endocrine neoplasia type 1 (MEN-1) is one of a group of disorders, the multiple endocrine neoplasias, that affect the endocrine system through development of neoplastic lesions in pituitary, parathyroid gland and pancreas. [ 1] Individuals suffering from this disorder are prone to developing multiple endocrine and nonendocrine tumors ...
RET receptor defect Which is growth signal receptor, its type of self-sufficiency of growth signals. Multiple endocrine neoplasia (abbreviated MEN) is a condition which encompasses several distinct syndromes featuring tumors of endocrine glands, each with its own characteristic pattern. In some cases, the tumors are malignant, in others, benign.
Glucagonoma is a very rare tumor of the alpha cells of the pancreas that results in the overproduction of the hormone glucagon. Typically associated with a rash called necrolytic migratory erythema, weight loss, and mild diabetes mellitus, most people with glucagonoma contract it spontaneously. [ 1] However, about 10% of cases are associated ...
Men and women have different fat distribution, and doctors already know that this can affect men’s risk of cardiovascular disease and type 2 diabetes. Men tend to develop type 2 diabetes earlier ...
Gastrinoma. Zollinger–Ellison syndrome ( Z-E syndrome) is rare disease in which tumors cause the stomach to produce too much acid, resulting in peptic ulcers. Symptoms include abdominal pain and diarrhea . The syndrome is caused by a gastrinoma, a neuroendocrine tumor that secretes a hormone called gastrin. [ 2]
Slowly evolving immune-mediated diabetes, or latent autoimmune diabetes in adults ( LADA ), is a form of diabetes that exhibits clinical features similar to both type 1 diabetes (T1D) and type 2 diabetes (T2D), [ 3][ 4] and is sometimes referred to as type 1.5 diabetes. [ 5] It is an autoimmune form of diabetes, similar to T1D, but patients ...
Gastrinomas are neuroendocrine tumors (NETs), usually located in the duodenum or pancreas, that secrete gastrin and cause a clinical syndrome known as Zollinger–Ellison syndrome (ZES). [ 1][ 2][ 3] A large number of gastrinomas develop in the pancreas or duodenum, with near-equal frequency, and approximately 10% arise as primary neoplasms in ...
A blue circle, the symbol for diabetes. High blood sugar levels, autoantibodies targeting insulin-producing cells. Type 1 diabetes ( T1D ), formerly known as juvenile diabetes, is an autoimmune disease that originates when cells that make insulin (beta cells) are destroyed by the immune system. [ 5] Insulin is a hormone required for the cells ...
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