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Free Guy is a 2021 American action comedy film directed and produced by Shawn Levy from a screenplay by Matt Lieberman and Zak Penn, and a story by Lieberman.The film stars Ryan Reynolds, Jodie Comer, Lil Rel Howery, Utkarsh Ambudkar, Joe Keery, and Taika Waititi.
Various collaborative online encyclopedias were attempted before the start of Wikipedia, but with limited success. [19] Wikipedia began as a complementary project for Nupedia, a free online English-language encyclopedia project whose articles were written by experts and reviewed under a formal process. [20]
Three of the four highest-grossing films, including Avatar at the top, were written and directed by James Cameron.. With a worldwide box-office gross of over $2.9 billion, Avatar is proclaimed to be the "highest-grossing" film, but such claims usually refer to theatrical revenues only and do not take into account home video and television income, which can form a significant portion of a film ...
Ferris Bueller's Day Off is a 1986 American teen comedy film written, co-produced, and directed by John Hughes. The film stars Matthew Broderick, Mia Sara, and Alan Ruck, with supporting roles from Jennifer Grey, Jeffrey Jones, Cindy Pickett, Edie McClurg, Lyman Ward, and Charlie Sheen.
(state flower) Gelsemium sempervirens: 1924 [59] Goldenrod (state wildflower) Solidago altissima: 2003 [60] South Dakota: Pasque flower: Pulsatilla hirsutissima: 1903 [61] Tennessee: Iris (state cultivated flower) Iris: 1933 [62] Purple passionflower (state wildflower 1) Passiflora incarnata: 1919 [62] Tennessee purple coneflower (state ...
People with type 1 diabetes tend to have more CD8+ T-cells and B-cells that specifically target islet antigens than those without type 1 diabetes, suggesting a role for the adaptive immune system in beta cell destruction. [63] [64] Type 1 diabetics also tend to have reduced regulatory T cell function, which may exacerbate autoimmunity. [63]
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