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Medical genetics. Named after. Donovan James McCune. Fuller Albright. McCune–Albright syndrome is a complex genetic disorder affecting the bone, skin and endocrine systems. It is a mosaic disease arising from somatic activating mutations in GNAS, which encodes the alpha-subunit of the G s heterotrimeric G protein. [ 1]
Minor dark circles and a hint of periorbital puffiness —a combination principally suggestive of minor sleep deprivation. Periorbital dark circles (including dark circles of the lower eyelid) are dark blemishes around the eyes. There are many causes of this symptom, including heredity and bruising. [1]
Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis. Melanin is a class of pigment responsible for producing color in the body in places such as the eyes, skin, and hair. The process of melanin synthesis (melanogenesis ...
Cardiology. Cherry angioma, also called cherry hemangioma [ 1] or Campbell de Morgan Spot, [ 2] is a small bright red dome-shaped bump on the skin. [ 3] It ranges between 0.5 – 6 mm in diameter and usually several are present, typically on the chest and arms, and increasing in number with age. [ 3][ 4] If scratched, they may bleed. [ 5]
Schamberg's disease, or progressive pigmented purpuric dermatosis, is a chronic discoloration of the skin which usually affects the legs and often spreads slowly. This disease is more common in males and may occur at any age from childhood onward. This condition is observed worldwide and has nothing to do with race or ethnic background.
Based on clinical examination, skin biopsy. Treatment. Electrodesiccation and curettage, cryotherapy. A seborrheic keratosis is a non-cancerous ( benign) skin tumour that originates from cells, namely keratinocytes, in the outer layer of the skin called the epidermis. Like liver spots, seborrheic keratoses are seen more often as people age. [ 4]
Pronunciation. pɪˈtiːkɪə. Specialty. Rheumatology. A petechia ( / pɪˈtiːkiə /; [ 1] pl.: petechiae) is a small red or purple spot (≤4 mm in diameter) that can appear on the skin, conjunctiva, retina, and mucous membranes which is caused by haemorrhage of capillaries. [ 2][ 3] The word is derived from Italian petecchia ' freckle ', of ...
Melasma. Melasma (also known as chloasma faciei, [ 1]: 854 or the mask of pregnancy[ 2] when present in pregnant women) is a tan or dark skin discoloration. Melasma is thought to be caused by sun exposure, genetic predisposition, hormone changes, and skin irritation. [ 3]
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