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Postinflammatory hyperpigmentation ( PIH) is a skin condition characterized by the darkening of the skin ( hyperpigmentation) following an inflammatory injury, such as acne, dermatitis, infectious disease, or trauma. Less frequently, it may occur as a complication of a medical procedure performed on the skin.
Medical genetics. Named after. Donovan James McCune. Fuller Albright. McCune–Albright syndrome is a complex genetic disorder affecting the bone, skin and endocrine systems. It is a mosaic disease arising from somatic activating mutations in GNAS, which encodes the alpha-subunit of the G s heterotrimeric G protein. [ 1]
Stevens–Johnson syndrome (SJS) is a type of severe skin reaction. [1] Together with toxic epidermal necrolysis (TEN) and Stevens–Johnson/toxic epidermal necrolysis (SJS/TEN) overlap, they are considered febrile mucocutaneous drug reactions and probably part of the same spectrum of disease, with SJS being less severe.
Urticaria pigmentosa is characterized by excessive amounts of mast cells in the skin. Red or brown spots are often seen on the skin, typically around the chest, forehead, and back. These mast cells, when irritated (e.g. by rubbing the skin, heat exposure), produce too much histamine, triggering an allergic reaction that leads to hives localized ...
Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis. Melanin is a class of pigment responsible for producing color in the body in places such as the eyes, skin, and hair. The process of melanin synthesis (melanogenesis ...
Mongolian spot is a congenital developmental condition—that is, one existing from birth—exclusively involving the skin. The blue colour is caused by melanocytes, melanin -containing cells, that are usually located in the surface of the skin (the epidermis ), but are in the deeper region (the dermis) in the location of the spot. [ 6]
Keratosis pilaris. Keratosis pilaris ( KP; also follicular keratosis, lichen pilaris, or colloquially chicken skin[ 1]) is a common, autosomal - dominant, genetic condition of the skin's hair follicles characterized by the appearance of possibly itchy, small, gooseflesh -like bumps, with varying degrees of reddening or inflammation. [ 2]
Cardiology. Cherry angioma, also called cherry hemangioma [ 1] or Campbell de Morgan Spot, [ 2] is a small bright red dome-shaped bump on the skin. [ 3] It ranges between 0.5 – 6 mm in diameter and usually several are present, typically on the chest and arms, and increasing in number with age. [ 3][ 4] If scratched, they may bleed. [ 5]