Search results
Results from the WOW.Com Content Network
Rare. Statin-associated autoimmune myopathy (SAAM), also known as anti-HMGCR myopathy, is a very rare form of muscle damage caused by the immune system in people who take statin medications. [ 1] However, there are cases of SAAM in patients who have not taken statin medication, and this can be explained by the exposure to natural sources of ...
Varenicline, sold under the brand names Chantix and Champix among others, is a medication used for smoking cessation [ 5][ 7] and for the treatment of dry eye disease. [ 6][ 8] It is a nicotinic acetylcholine receptor partial agonist. [ 5][ 6] When activated, this receptor releases dopamine in the nucleus accumbens, the brain's reward center ...
CHANTIX ® (varenicline) Demonstrates Efficacy in Smokers Who Previously Attempted to Quit Smoking with CHANTIX New Positive Top-line Results in Adult Smokers Re-treated With CHANTIX NEW YORK ...
Myostatin inhibitor. Myostatin inhibitors are a class of drugs that work by blocking the effects of myostatin, which inhibits muscle growth. In animal models and limited human studies, myostatin inhibitors have increased muscle size. They are being developed to treat obesity, sarcopenia, muscular dystrophy, and other illnesses.
On Thursday, Pfizer announced the results of a study of the safety and effectiveness of its Chantix smoking-cessation drug on relapsed smokers. The prognosis was good. Over the course of 12 weeks ...
For those truly addicted to smoking, the frustrations of quitting go well beyond mental fortitude. Now, scientists say a strategy based on how your body breaks down nicotine might be the best way ...
Myostatin is a myokine that is produced and released by myocytes and acts on muscle cells to inhibit muscle growth. [ 7] Myostatin is a secreted growth differentiation factor that is a member of the TGF beta protein family. [ 8][ 9] Myostatin is assembled and produced in skeletal muscle before it is released into the blood stream. [ 10]
HMG-CoA reductase ( 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase, official symbol HMGCR) is the rate-controlling enzyme (NADH-dependent, EC 1.1.1.88; NADPH-dependent, EC 1.1.1.34) of the mevalonate pathway, the metabolic pathway that produces cholesterol and other isoprenoids. HMGCR catalyzes the conversion of HMG-CoA to mevalonic acid, a ...