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Discover what this essential B vitamin can do for your body and whether you need more in your diet.
Research from 2018 links calcium carbonate to constipation, bloating, abdominal pain and diarrhea. A 2012 research review found that constipation was a commonly reported side effect of calcium ...
Biotin is available in dietary supplements, which may contain biotin only or a combination of B-complex vitamins. “Most people do not require a biotin supplement ,” says Largeman-Roth.
Subclinical deficiency can cause mild symptoms, such as hair thinning, brittle fingernails, or skin rash, typically on the face. [2] [4] Aside from inadequate dietary intake (rare), biotin deficiency can be caused by a genetic disorder that affects biotin metabolism. The most common among these is biotinidase deficiency.
Mutations in the BTD gene cause biotinidase deficiency. Biotinidase is the enzyme that is made by the BTD gene. Many mutations that cause the enzyme to be nonfunctional or to be produced at extremely low levels have been identified. Biotin is a vitamin that is chemically bound to proteins. (Most vitamins are only loosely associated with proteins.)
Hypervitaminosis is a condition of abnormally high storage levels of vitamins, which can lead to various symptoms as over excitement, irritability, or even toxicity. Specific medical names of the different conditions are derived from the given vitamin involved: an excess of vitamin A , for example, is called hypervitaminosis A .
Still, some people may experience cramping, nausea, acne breakouts, and an allergic reaction that results in a skin rash, per Cleveland Clinic. One important note: Excess biotin can also "cause ...
Therefore, all patients receiving TPN must also receive biotin at the recommended daily dose, especially if TPN therapy is expected to last more than 1 week. All hospital pharmacies currently include biotin in TPN preparations. [2] Protein deficiency (not certain): A shortage of proteins involved in biotin homeostasis can cause biotin deficiency.