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Pregnancy after the age of 35 augments the risk of VTE, as does multigravidity of more than four pregnancies. [2] Pregnancy in itself causes approximately a five-fold increased risk of deep venous thrombosis. [6] Several pregnancy complications, such as pre-eclampsia, cause substantial hypercoagulability. [2]
[11] [12] [13] Maternal valproate use during pregnancy increased the probability of autism in the offspring compared to mothers not taking valproate from 1.5% to 4.4%. [14] A 2005 study found rates of autism among children exposed to sodium valproate before birth in the cohort studied were 8.9%. [15]
DVT risk can be altered by abnormalities in the cascade. The regulators, antithrombin (ᾳTHR) and activated protein C (APC), are shown in green above the clotting factors they affect. Dozens of genetic risk factors have been identified, [14] and they account for approximately 50 to 60% of the variability in VTE rates. [4]
Some research suggests that a particularly intense immune reaction during gestation might increase the risk of neurodevelopmental ... increase the risk of neurodevelopmental disorders like autism.
Several prenatal and perinatal complications have been reported as possible risk factors for autism. These risk factors include maternal gestational diabetes, maternal and paternal age over 30, [198] [199] [200] bleeding during pregnancy after the first trimester, use of certain prescription medication (e.g. valproate) during pregnancy, and ...
The researchers examined the fish intake of 10,800 pregnant women and the fish oil supplementation of 12,646 pregnant women for associations with autism diagnoses and parent-reported autism ...
A combination of pregnancy-exacerbated hypercoagulability and additional risk factors such as obesity and thrombophilias makes pregnant women vulnerable to thrombotic events [29] T.he prophylactic measures that include the usage of low molecular weight heparin, in fact, can significantly reduce risks associated with surgery, particularly in ...
After adjusting for factors such as mother’s age, smoking status and maternal diagnoses of autism, ADHD and intellectual disability, the researchers found that among those children whose mothers ...
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