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The dermis is composed of three major types of cells: [3] fibroblasts, macrophages, and mast cells.. Apart from these cells, the dermis is also composed of matrix components such as collagen (which provides strength), elastin (which provides elasticity), and extrafibrillar matrix, an extracellular gel-like substance primarily composed of glycosaminoglycans (most notably hyaluronan ...
The reticular layer is the deep layer of the dermis and consists of the dense irregular connective tissue. These layers serve to give elasticity to the integument, allowing stretching and conferring flexibility, while also resisting distortions, wrinkling, and sagging. [3] The dermal layer provides a site for the endings of blood vessels and ...
This type of connective tissue is found mostly in the reticular layer (or deep layer) of the dermis. [3] It is also in the sclera and in the deeper skin layers. Due to high portions of collagenous fibers, dense irregular connective tissue provides strength, making the skin resistant to tearing by stretching forces from different directions.
The dermis is the layer of skin between the epidermis and subcutaneous tissue, and comprises two sections, the papillary dermis and the reticular dermis. [10] The superficial papillary dermis interdigitates with the overlying rete ridges of the epidermis, between which the two layers interact through the basement membrane zone. [10]
The dermis is the layer of skin between the epidermis and subcutaneous tissue, and comprises two sections, the papillary dermis and the reticular dermis. [24] The superficial papillary dermis interdigitates with the overlying rete ridges of the epidermis, between which the two layers interact through the basement membrane zone. [ 24 ]
Level 2: Invasion into the papillary dermis; Level 3: Invasion to the junction of the papillary and reticular dermis; Level 4: Invasion into the reticular dermis; Level 5: Invasion into subcutaneous tissue.
The dermis is the layer of skin beneath the epidermis that consists of connective tissue and cushions the body from stress and strain. The dermis provides tensile strength and elasticity to the skin through an extracellular matrix composed of collagen fibrils , microfibrils , and elastic fibers , embedded in hyaluronan and proteoglycans . [ 15 ]
At the electron microscopic level, the oxytalan fibers are formed by bundles of tubular microfibrils 10 to 12 nm in diameter. In the deepest layers of the dermis, an amorphous material is seen in the core of these bundles. In the elaunin fibers, the amorphous material is sparse, while in the elastic fibers, it is abundant and compact." [2]