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In addition, LDLR modulation is associated with early atherosclerosis-related lymphatic dysfunction. [27] Synthesis of receptors in the cell is regulated by the level of free intracellular cholesterol; if it is in excess for the needs of the cell then the transcription of the receptor gene will be inhibited. [ 28 ]
Indolent lymphoma, also known as low-grade lymphoma, is a group of slow-growing non-Hodgkin lymphomas (NHLs). [3] Because they spread slowly, they tend to have fewer signs and symptoms when first diagnosed and may not require immediate treatment.
Signs and symptoms are not mutually exclusive, for example a subjective feeling of fever can be noted as sign by using a thermometer that registers a high reading. [7] Because many symptoms of cancer are gradual in onset and general in nature, cancer screening (also called cancer surveillance) is a key public health priority. This may include ...
B symptoms are so called because Ann Arbor staging of lymphomas includes both a number (I–IV) and a letter (A or B). [1] "A" indicates the absence of systemic symptoms, while "B" indicates their presence. B symptoms include: Fever greater than 38 °C.
Chronic lymphocytic leukemia (CLL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell). [2] [8] Early on, there are typically no symptoms. [2] Later, non-painful lymph node swelling, feeling tired, fever, night sweats, or weight loss for no clear reason may occur.
The early stage of the disease often causes no symptoms, which is why the cancer is so deadly: It’s usually caught only when it becomes large and spreads outside of the gland.
Pancreatic cancer is a type of cancer that starts in the pancreas, an organ that sits behind the stomach and is shaped like a fish with a wide head, a tapering body, and a narrow, pointed tail ...
There are a few possible causes of resistance in cancer, one of which is the presence of small pumps on the surface of cancer cells that actively move chemotherapy from inside the cell to the outside. Cancer cells produce high amounts of these pumps, known as p-glycoprotein, in order to protect themselves from chemotherapeutics. Research on p ...