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Sialadenitis can be further classed as acute or chronic. Acute sialadenitis is an acute inflammation of a salivary gland which may present itself as a red, painful swelling that is tender to touch. Chronic sialadenitis is typically less painful but presents as recurrent swellings, usually after meals, without redness. [1]
Chronic sclerosing sialadenitis is a chronic (long-lasting) inflammatory condition affecting the salivary gland.Relatively rare in occurrence, this condition is benign, but presents as hard, indurated and enlarged masses that are clinically indistinguishable from salivary gland neoplasms or tumors.
Mumps is the most common viral sialadenitis. It usually occurs in children and involves pain in front of the ear, swelling of the parotid, fever, chills, and headaches. [2] Bacterial sialadenitis is usually caused by ascending organisms from the mouth. Risk factors include reduced salivary flow.
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Strictures are the second most common cause of chronic obstructive sialadenitis, after salivary stones. [1] In line with this, strictures may give rise to the "meal time syndrome", [1] where there is pain and swelling of the involved salivary gland upon salivary stimulation with the sight, smell and taste of food.
Sialolithiasis may also develop because of the presence of existing chronic infection of the glands, dehydration (e.g. use of phenothiazines), Sjögren's syndrome and/or increased local levels of calcium, but in many instances the cause is idiopathic (unknown).
Micrograph of chronic inflammation of the salivary gland sialadenitis Main article: Salivary gland disease A sialolithiasis (a salivary calculus or stone) may cause blockage of the ducts, most commonly the submandibular ducts, causing pain and swelling of the gland.
Lymphoepithelial sialadenitis, also termed chronic sialadenitis, is a benign infiltration of salivary glands by B-cells with morphological features of marginal zone B-cells, centrocytes, and monocytes.