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Neurosyphilis is the infection of the central nervous system by Treponema pallidum, the bacterium that causes the sexually transmitted infection syphilis. In the era of modern antibiotics , the majority of neurosyphilis cases have been reported in HIV-infected patients.
Tabes dorsalis is a late consequence of neurosyphilis, characterized by the slow degeneration (specifically, demyelination) of the neural tracts primarily in the dorsal root ganglia of the spinal cord (nerve root). These patients have lancinating nerve root pain which is aggravated by coughing, and features of sensory ataxia with ocular ...
Meningeal syphilis (as known as syphilitic aseptic meningitis or meningeal neurosyphilis) is a chronic form of syphilis infection that affects the central nervous system. Treponema pallidum , a spirochate bacterium, is the main cause of syphilis, which spreads drastically throughout the body and can infect all its systems if not treated ...
General paresis, also known as general paralysis of the insane (GPI), paralytic dementia, or syphilitic paresis is a severe neuropsychiatric disorder, classified as an organic mental disorder, and is caused by late-stage syphilis and the chronic meningoencephalitis and cerebral atrophy that are associated with this late stage of the disease when left untreated.
Malaria as a treatment for syphilis was usually reserved for late disease, especially neurosyphilis, and then followed by either Salvarsan or Neosalvarsan as adjuvant therapy. This discovery was championed by Julius Wagner-Jauregg , [ 77 ] who won the 1927 Nobel Prize for Medicine for his discovery of the therapeutic value of malaria ...
Discography is the study and cataloging of published sound recordings, often by specified artists or within identified music genres.The exact information included varies depending on the type and scope of the discography, but a discography entry for a specific recording will often list such details as the names of the artists involved, the time and place of the recording, the title of the ...
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Year Album details Chart positions US Hard [1]US Heat [2]US Rock [3]US Taste [4]1987 Pain of Mind. Released: 1987; Label: Alchemy Records; Format: LP — — — — 1990