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Zonisamide is an antiseizure drug chemically classified as a sulfonamide and unrelated to other antiseizure agents. The precise mechanism by which zonisamide exerts its antiseizure effect is unknown, although it is believed that the drug blocks sodium and T-type calcium channels , which leads to the suppression of neuronal hypersynchronization ...
Ethosuximide, sold under the brand name Zarontin among others, is a medication used to treat absence seizures. [4] It may be used by itself or with other antiseizure medications such as valproic acid. [4]
Bupropion/zonisamide (former tentative brand name Empatic, Excalia) is an experimental combination of bupropion which was under development for the treatment of obesity. [1] [2] [3] Bupropion is a norepinephrine–dopamine reuptake inhibitor and nicotinic acetylcholine receptor antagonist, while zonisamide is an anticonvulsant acting as a sodium channel blocker, T-type calcium channel blocker ...
This can help you move toward a healthy weight and make weight management easier. It’s pretty effective too. A 2023 systematic review looked at 10 studies with almost 10,000 participants in total.
"The added sugars can increase a toddler's preference for sweetened foods, contributing to obesity and other health risks throughout their lives," noted Fuchs, who led the AAP report on toddler milks.
Morgan Metzer survived a violent attack in her Canton, Georgia, home by an assailant she described as dressed in black and sounding like Batman. The only thing more surprising than the attack ...
Microsoft Forms (formerly Office 365 Forms) is an online survey creator, ... Due to a wave of phishing attacks utilizing Microsoft 365 in early 2021, [6] ...
There is some evidence that rufinamide can modulate the gating of voltage-gated sodium channels, [8] [9] a common target for antiepileptic drugs. [10] A recent study indicates subtle effects on the voltage-dependence of gating and the time course of inactivation in some sodium channel isoforms that could reduce neuronal excitability. [ 11 ]