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Remyelination is the process of propagating oligodendrocyte precursor cells to form oligodendrocytes to create new myelin sheaths on demyelinated axons in the Central nervous system (CNS). This is a process naturally regulated in the body and tends to be very efficient in a healthy CNS. [ 1 ]
The process of generating myelin is called myelination or myelinogenesis. In the CNS, oligodendrocyte progenitor cells (OPCs) differentiate into mature oligodendrocytes, which form myelin. In humans, myelination begins early in the 3rd trimester, [ 11 ] although only little myelin is present in either the CNS or the PNS at the time of birth.
Spontaneous recovery is associated with the learning process called classical conditioning, in which an organism learns to associate a neutral stimulus with a stimulus which produces an unconditioned response. As a result, the previously neutral stimulus comes to produce its own response, which is usually similar to that produced by the ...
An example of this mode of migration is in GnRH-expressing neurons, which make a long journey from their birthplace in the nose, through the forebrain, and into the hypothalamus. [19] Many of the mechanisms of this migration have been worked out, starting with the extracellular guidance cues [ 20 ] that trigger intracellular signaling.
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N-cadherin is expressed in regions of active remyelination and may play an important role in generating a local environment conducive to remyelination. [24] N-cadherin agonists have been identified and observed to stimulate neurite growth and cell migration, key aspects of promoting axon growth and remyelination after injury or disease.
Subscribe to Yahoo Fantasy Forecast on Apple Podcasts, Spotify, YouTube or wherever you listen.. Round 4: James Cook, RB, Buffalo Bills. ADP: 40.8, RB14 PPG finish: RB9. Despite being the RB1 for ...