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Sometimes these species are referred to as "gold salts". "Chrysotherapy" and "aurotherapy" are the applications of gold compounds to medicine. [1] Research on the medicinal effects of gold began in 1935, [2] primarily to reduce inflammation and to slow disease progression in patients with rheumatoid arthritis. The use of gold compounds has ...
Gold: Gold salt complexes have been used to treat rheumatoid arthritis (Figure 3). The gold salts are believed to interact with albumin and eventually be taken up by immune cells, triggering anti-mitochondrial effects and eventually cell apoptosis. This is an indirect treatment of arthritis, mitigating the immune response.
Most drugs based on gold are Au(I) derivatives. [3] Au(III) (referred to as the auric) is a common oxidation state, and is illustrated by gold(III) chloride, Au 2 Cl 6. The gold atom centers in Au(III) complexes, like other d 8 compounds, are typically square planar, with chemical bonds that have both covalent and ionic character.
Sodium aurothiomalate (INN, known in the United States as gold sodium thiomalate) is a gold compound that is used for its immunosuppressive anti-rheumatic effects. [ 2 ] [ 3 ] Along with an orally-administered gold salt, auranofin , it is one of only two gold compounds currently employed in modern medicine.
Pages in category "Gold compounds" The following 13 pages are in this category, out of 13 total. This list may not reflect recent changes. ...
Organogold chemistry is the study of compounds containing gold–carbon bonds. They are studied in academic research, but have not received widespread use otherwise. The dominant oxidation states for organogold compounds are I with coordination number 2 and a linear molecular geometry and III with CN = 4 and a square planar molecular geometry ...
Gold thioglucose features gold in the oxidation state of +I, like other gold thiolates. It is a water-soluble, non-ionic species that is assumed to exist as a polymer. [ 1 ] Under physiological conditions, an oxidation-reduction reaction leads to the formation of metallic gold and sulfinic acid derivative of thioglucose.
Sodium aurothiosulfate, or sanocrysin, is the inorganic compound with the formula Na 3 [Au(S 2 O 3) 2]·2H 2 O. It is the trisodium salt of the coordination complex of gold(I), [Au(S 2 O 3) 2] 3−. The dihydrate, which is colorless, crystallizes with two waters of crystallization. The compound has some medicinal properties as well as potential ...