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Ovarian hyperstimulation syndrome (OHSS) is a medical condition that can occur in some women who take fertility medication to stimulate egg growth, and in other women in sporadic cases. Most cases are mild, but rarely the condition is severe and can lead to serious illness or even death.
In rare cases, OHSS can kidney failure as well as blood clots; in very rare cases, OHSS can be life-threatening: In 2022, a 23-year-old woman from India died during an IVF procedure as OHSS caused ...
Any developing signs of OHSS will typically vanish at that point. However, in rare cases, severe OHSS can continue to develop. Reduced success rates have been reported in fresh embryo transfers when the agonist trigger is used without hCG, so that most centers will freeze all embryos in cycles triggered only with the agonist.
OHSS is characterized as cystic enlargement of the ovaries. Multiple birth is especially deleterious due to compounding risks including premature delivery and low birthweight, pre-eclampisa, and increased risk of neonatal mortality. While triplet births have been declining in ART, multiple births remain over 50% of births from IVF.
Among the health risks to donors, the Practice Committee of the American Society for Reproductive Medicine (ASRM) lists ovarian hyperstimulation syndrome (OHSS), which can be life-threatening in ...
Out of in vitro matured oocytes, those fertilised with ICSI have a success rates of 60-80%, compared to IVF with success rates of 25-40%. [16] A few live births have already been made by taking small early tertiary follicles, letting them mature in vitro and subsequently fertilizing them. However, for follicles that haven't reached the early ...
The estimated average cost per IVF cycle is about $12,000, according to the American Society for Reproductive Medicine (ASMR). But gynecologist Karen Tang, M.D., previously told USA TODAY that it ...
A Cochrane review estimated that using GnRH agonist instead of hCG in IVF decreases the risk of mild, moderate or severe OHSS with an odds ratio of approximately 0.15. The review estimated that, for a woman with a 5% risk of mild, moderate or severe OHSS with the use of HCG, the risk of OHSS with the use of a GnRH agonist would be between 0 and ...
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