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Opioids' classical use besides pain relief is as an anti-diarrhoeal drug. Opioids have agonist actions on the intestinal opioid receptors, which when activated cause constipation . Drugs such as morphine or codeine can be used to relieve diarrhoea this way.
Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, migraines, or surgery. [8] It is also effective for treating gastroenteritis. [9] [10] It can be given orally (by mouth), intramuscularly (injection into a muscle), or intravenously ...
If possible, alternate medications should be prescribed that avoid the side effect of constipation. [citation needed] Given that all opioids can cause constipation, [6] it is recommended that any patient placed on opioid pain medications be given medications to prevent constipation before it occurs. Daily medications can also be used to promote ...
In a similar sense, we want to get to the roots contributing to constipation to find lasting relief." According to Sanmiguel, certain lifestyle changes can lead to long-lasting constipation relief.
Constipation is a bowel dysfunction that makes bowel movements infrequent or hard to pass. [2] The stool is often hard and dry. [4] Other symptoms may include abdominal pain, bloating, and feeling as if one has not completely passed the bowel movement. [3]
Prucalopride is contraindicated where there is hypersensitivity to the active substance or to any of the excipients, renal impairment requiring dialysis, intestinal perforation or obstruction due to structural or functional disorder of the gut wall, obstructive ileus, severe inflammatory conditions of the intestinal tract, such as Crohn's disease, and ulcerative colitis and toxic megacolon ...
This neurological problem can also result in reduced sensation of rectal filling and weakness of the anal sphincter because of weak muscular contraction so can cause stool leakage. [12] In patients with multiple sclerosis, constipation and fecal incontinence often coexist, and they can be acute, chronic or intermittent due to the fluctuating ...
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