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Other causes are side effects of topical decongestants such as oxymetazoline and phenylephrine. Both of these medications activate alpha-1 adrenergic receptors that result in smooth muscle constriction. Non-selective beta blockers are known to facilitate bronchospasm as well. Beta blockers bind to the β2 receptors and block the action of ...
The most common cause of emphysema is smoking and smoking cessation is mandatory if this incurable disease is to be treated. Prevention of bronchoconstriction by this pathway is vital for people with emphysema and there are several anticholinergic medications that in combination with mucous thinning agents such as Guaifenesin cause significant ...
The issue of bronchospasm acquired prominence in the neuromuscular-blocking agents arena after the withdrawal from clinical use of rapacuronium (Raplon - a steroidal neuromuscular-blocking agent marketed by Organon) in 2001 [9] [10] after several serious events of bronchospasm, [11] [12] including five unexplained fatalities, [13] following its ...
Bronchial hyperresponsiveness is a hallmark of asthma but also occurs frequently in people with chronic obstructive pulmonary disease (COPD). [2] In the Lung Health Study, bronchial hyperresponsiveness was present in approximately two-thirds of patients with non-severe COPD, and this predicted lung function decline independently of other ...
Aspirin-exacerbated respiratory disease (AERD), also called NSAID-exacerbated respiratory disease (N-ERD) or historically aspirin-induced asthma and Samter's Triad, is a long-term disease defined by three simultaneous symptoms: asthma, chronic rhinosinusitis with nasal polyps, and intolerance of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs).
Beta blocker medications such as propranolol can trigger asthma in those who are susceptible. [85] Cardioselective beta-blockers, however, appear safe in those with mild or moderate disease. [86] [87] Other medications that can cause problems in asthmatics are angiotensin-converting enzyme inhibitors, aspirin, and NSAIDs. [88]
Salbutamol is typically used to treat bronchospasm (due to any cause—allergic asthma or exercise-induced), as well as chronic obstructive pulmonary disease. [8] It is also one of the most common medicines used in rescue inhalers (short-term bronchodilators to alleviate asthma attacks). [17] As a β 2 agonist, salbutamol also has use in ...
More severe effects include paradoxical bronchospasm, hypokalemia, and in rare cases a myocardial infarction. [4] More severe effects, such as pulmonary edema , myocardial ischemia , and cardiac arrhythmia , are exceptional.) [ 6 ] [ 7 ] [ 1 ]