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Peripheral artery disease most commonly affects the legs, but other arteries may also be involved, such as those of the arms, neck, or kidneys. [4] [17] Peripheral artery disease (PAD) is a form of peripheral vascular disease. Vascular refers to the arteries and veins within the body. PAD differs from peripheral veinous disease. PAD means the ...
Peripheral artery disease (PAD), or limb ischemia, affects the femoral, popliteal, or iliac arteries. [17] PAD is caused by atherosclerotic plaques that occlude blood flow to extremities. [5] Once blood flow is impeded, ischemic muscle cells switch from aerobic to anaerobic metabolism to cope with oxygen scarcity.
The primary prevention of acute limb ischemia starts with awareness of peripheral artery disease (PAD). In patients with PAD, smoking cessation, weight control, blood pressure control, diabetes control, physical activity, and rhythm control in those with atrial fibrillation should be encouraged. [ 20 ]
Ischemia is a vascular disease involving an interruption in the arterial blood supply to a tissue, organ, or extremity that, if untreated, can lead to tissue death. It can be caused by embolism, thrombosis of an atherosclerotic artery, or trauma. Venous problems like venous outflow obstruction and low-flow states can cause acute arterial ischemia.
Chronic limb threatening ischemia (CLTI), also known as critical limb ischemia (CLI), is an advanced stage of peripheral artery disease (PAD). It is defined as ischemic rest pain, arterial insufficiency ulcers , and gangrene .
Atherosclerosis, by definition, affects only medium and large arteries (excluding arterioles). Macrovascular disease is associated with the development of coronary artery disease , peripheral vascular disease , brain attack ( stroke ), and increased risk of infection.
Blood vessel disorder generally refers to the narrowing, hardening or enlargement of arteries and veins. It is often due to the build-up of fatty deposits in the lumen of blood vessels or infection of the vessel wall. This can occur in various locations such as coronary blood vessels, peripheral arteries and veins.
Intermittent claudication, also known as vascular claudication, is a symptom that describes muscle pain on mild exertion (ache, cramp, numbness or sense of fatigue), [1] classically in the calf muscle, which occurs during exercise, such as walking, and is relieved by a short period of rest.
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