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Modern complete blood count analyzers can provide an automated white blood cell differential, but they have a limited ability to differentiate immature and abnormal cells, so manual examination of the blood smear is frequently indicated. [5] [6] Blood smear examination is the preferred diagnostic method for certain parasitic infections, such as ...
Peripheral blood smear in patient with thrombotic thrombocytopenic purpura. Typical schistocytes are annotated. A schistocyte (from Greek schistos for "divided" and kytos for "hollow" or "cell") is a fragmented part of a red blood cell. Schistocytes are sometimes referred to as helmet cells because of their irregular shape from mechanical force ...
Along with Döhle bodies and toxic vacuolation, which are two other findings in the cytoplasm of granulocytes, toxic granulation is a peripheral blood film finding suggestive of an inflammatory process. [1] Toxic granulation is often found in patients with bacterial infection and sepsis, [1] [2] although the finding is nonspecific. [3]
A white blood cell differential is a medical laboratory test that provides information about the types and amounts of white blood cells in a person's blood. The test, which is usually ordered as part of a complete blood count (CBC), measures the amounts of the five normal white blood cell types – neutrophils, lymphocytes, monocytes, eosinophils and basophils – as well as abnormal cell ...
Blood smear from a person with iron deficiency anemia, displaying characteristic red blood cell morphology. The red blood cells are abnormally small (microcytosis), have large areas of central pallor (hypochromia), and vary greatly in size (anisocytosis). An abnormally low hemoglobin, hematocrit, or red blood cell count indicates anemia. [119]
Rare elliptocytes (less than 1%) on a peripheral blood smear are a normal finding. [citation needed] These abnormal red blood cells are seen in higher numbers in the blood films of patients with blood disorders such as: [4] Hereditary elliptocytosis and Southeast Asian ovalocytosis; Thalassemia; Iron deficiency; Myelodysplastic syndrome and ...
In vivo (within the blood vessel), the codocyte is a bell-shaped cell. It assumes a "target" configuration only when processed to obtain a blood film. In the film these cells appear thinner than normal, primarily due to their pallor (by which thickness is judged on microscopy).
Poikilocytosis may be diagnosed with a test called a blood smear. During a blood smear, a medical technologist/clinical lab scientist spreads a thin layer of blood on a microscope slide and stains the blood to help differentiate the cells. The technologist/clinical lab scientist then views the blood under a microscope, where the sizes and ...