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Nature Structural & Molecular Biology is a monthly peer-reviewed scientific journal publishing research articles, reviews, news, and commentaries in structural and molecular biology, with an emphasis on papers that further a "functional and mechanistic understanding of how molecular components in a biological process work together".
Bik Kwoon Yeung Tye (Chinese: 戴楊碧瓘; born c. 1947) is a Chinese-American molecular geneticist and structural biologist.Tye's pioneering work on eukaryotic DNA replication led to the discovery of the minichromosome maintenance (MCM) genes in 1984, [1] which encode the catalytic core of the eukaryotic replisome.
A group of 38 scientists working in nine countries has sounded an alarm about the potential creation of mirror bacteria — synthetic organisms in which the molecular structure found in nature is ...
Currently, solid-state NMR is widely used in the field of structural biology to determine the structure and dynamic nature of proteins (protein NMR). [ 15 ] In 1990, Richard Henderson produced the first three-dimensional, high resolution image of bacteriorhodopsin using cryogenic electron microscopy (cryo-EM). [ 16 ]
Xiang-Lei Yang (杨湘磊) is a Chinese-born American molecular biologist. She is a professor at The Scripps Research Institute, located in La Jolla, California. [1] Her work has contributed to the establishment of physiological importance of aminoacyl-tRNA synthetases beyond their classical role in supporting mRNA translation and their disordered processes that contribute to disease.
[3] [4] In 2020, she reported, also in Nature [5] the first methyltransferase ribozyme (MTR1), and published its structure and mechanism in 2022. [6] The discovery of the methyltransferase ribozyme provides clues to the catalytic abilities of RNA, which may have played an important role during early evolution.
She also served as Head, Departments of Biochemistry and Medical Chemistry, School of Molecular and Cellular Biology, University of Illinois from 2009-2013 and 2014-2018 serving as Interim Associate Dean for the Sciences in the College of Liberal Arts and Sciences, University of Illinois 2013.
A few of his lab's notable scientific contributions include the structural and molecular mechanism of DNA end resection by RecBCD [4] (E. coli) and DNA2-Sgs1-RPA and regulatory stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2 [5] (S. cerevisiae), the kinetics of RecA filament nucleation and growth [6] and regulation by RecFOR [7] (E. coli), the ...