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Drug-induced lupus erythematosus is an autoimmune disorder caused by chronic use of certain drugs. These drugs cause an autoimmune response (the body attacks its own cells) producing symptoms similar to those of systemic lupus erythematosus (SLE).
Drug-induced lupus erythematosus is a (generally) reversible condition that usually occurs in people being treated for a long-term illness. Drug-induced lupus mimics SLE. However, symptoms of drug-induced lupus generally disappear once the medication that triggered the episode is stopped.
Lupus erythematosus may manifest as systemic disease or in a purely cutaneous form also known as incomplete lupus erythematosus. Lupus has four main types: [citation needed] systemic; discoid; drug-induced; neonatal; Of these, systemic lupus erythematosus (also known as SLE) is the most common and serious form.
Around 90% of people with lupus are women. Common symptoms include extreme fatigue, joint pain or skin rashes. ... The study found that giving people with lupus anifrolumab, a drug that blocks ...
The oral drug, brepocitinib, did not meet the primary study goal of reduction in disease activity at week 52 in patients of SLE, in which the immune system that normally helps protect the body ...
The British drugmaker said anifrolumab under the TULIP 2 program helped patients with systemic lupus erythematosus, commonly known as SLE. The drug had failed to meet its main goal in the final ...
Although there are no established criteria for diagnosing drug-induced SLE, most reports used the following criteria: afflicted individuals had a sufficient and continuing exposure to the drug, at least one symptom seen in SLE, no history of SLE symptoms before starting the drug, and resolution of their drug-induced symptom(s) within weeks or ...
The etiology of systemic lupus erythematosus is not well understood. Sunlight exposure is the traditional precipitating factor in patients with immune dysregulation and an aberrant milieu of genetic predisposition. There have also been reports of drug-induced SCLE.
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