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2. Trimethoprim/sulfamethoxazole - Wikipedia

   en.wikipedia.org/wiki/Trimethoprim/sulfamethoxazole

   The synergy between trimethoprim and sulfamethoxazole was first described in the late 1960s. [25] [26] [27] Trimethoprim and sulfamethoxazole have a greater effect when given together than when given separately, because they inhibit successive steps in the folate synthesis pathway. They are given in a one-to-five ratio in their tablet ...

3. Urinary anti-infective agent - Wikipedia

   en.wikipedia.org/wiki/Urinary_anti-infective_agent

   Urinary tract infection in pediatric patients is a significant clinical issue, affecting approximately 7% of fevered infants and children. [43] If left untreated, the infection can ascend from the bladder to the kidneys, resulting in acute pyelonephritis, which leads to hypertension , kidney scarring , and end-stage kidney disease .

4. Trimethoprim - Wikipedia

   en.wikipedia.org/wiki/Trimethoprim

   Trimethoprim (TMP) is an antibiotic used mainly in the treatment of bladder infections. [1] Other uses include for middle ear infections and travelers' diarrhea. [1] With sulfamethoxazole or dapsone it may be used for Pneumocystis pneumonia in people with HIV/AIDS.

5. List of side effects of trimethoprim/sulfamethoxazole - Wikipedia

   en.wikipedia.org/.../sulfamethoxazole

   Megaloblastic anaemia; Methaemoglobinaemia; Erythema multiforme; Low blood sugar; Hepatitis (liver swelling); Crystalluria (crystals in the urine); Urinary obstruction causing difficulty passing urine

6. Urinary tract infection - Wikipedia

   en.wikipedia.org/wiki/Urinary_tract_infection

   A urinary tract infection (UTI) is an infection that affects a part of the urinary tract. [1] Lower urinary tract infections may involve the bladder ( cystitis ) or urethra ( urethritis ) while upper urinary tract infections affect the kidney ( pyelonephritis ). [ 10 ]

7. Staphylococcus saprophyticus - Wikipedia

   en.wikipedia.org/wiki/Staphylococcus_saprophyticus

   Staphylococcus saprophyticus urinary tract infections are usually treated with trimethoprim-sulfamethoxazole or with a quinolone such as to be alone norfloxacin. [3] It has also been shown to be susceptible to ampicillin & ceftriaxone. [9]