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A bronchial challenge test is a medical test used to assist in the diagnosis of asthma. [1] The patient breathes in nebulized methacholine or histamine. Thus the test may also be called a methacholine challenge test or histamine challenge test respectively. Both drugs provoke bronchoconstriction, or narrowing of the airways.
Methacholine is primarily used to diagnose bronchial hyperreactivity, [1] which is the hallmark of asthma and also occurs in chronic obstructive pulmonary disease. This is accomplished through the bronchial challenge test , or methacholine challenge, in which a subject inhales aerosolized methacholine, leading to bronchoconstriction .
Medication challenge tests, such as the methacholine challenge test, have a lower sensitivity for detection of exercise-induced bronchoconstriction in athletes and are also not a recommended first-line approach in the evaluation of exercise-induced asthma. [13] Mannitol inhalation [14] [15] has been recently approved for use in the United States.
The specific inhalation challenge (SIC) is a diagnosis tool to assess airway responsiveness to "sensitizing" substances as opposed to nonspecific stimuli such as pharmacological agents (i.e. histamine, methacholine), cold air and exercise. [1]
Canada wants to deepen its economic ties with the EU and uphold global trading rules in the face of threatened U.S. tariffs, its trade minister Mary Ng told Reuters on Saturday. The EU and Canada ...
“I’m a mess,” he said in a phone interview. “I’m so angry. I don’t even know how to explain this to you. I’m so angry with her for the decision that was made,” he said.
The basic forced volume vital capacity (FVC) test varies slightly depending on the equipment used. It can be in the form of either closed or open circuit. Regardless of differences in testing procedure providers are recommended to follow the ATS/ERS Standardisation of Spirometry. The standard procedure ensures an accurate and objectively ...
Thursday's Cactus League opener, a 12-4 Cubs win, saw the first use of an automated ball-strike challenge system, commonly known as a "robot ump," between MLB teams. The Cubs used the challenge ...