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The CcdA/CcdB Type II Toxin-antitoxin system is one example of the bacterial toxin-antitoxin (TA) systems that encode two proteins, one a potent inhibitor of cell proliferation (toxin) and the other its specific antidote (antitoxin). These systems preferentially guarantee growth of plasmid -carrying daughter cells in a bacterial population by ...
An antidote is a substance that can counteract a form of poisoning. [ 1 ] The term ultimately derives from the Greek term φάρμακον ἀντίδοτον (pharmakon antidoton), " (medicine) given as a remedy". Antidotes for anticoagulants are sometimes referred to as reversal agents. [ 2 ]
Strychnos toxifera, the Strychnos species which is the principal source of 'calabash curare' and its main active constituent, the alkaloid toxiferine. Curare (/ kʊˈrɑːri / or / kjʊˈrɑːri /; kuu-RAH-ree or kyuu-RAH-ree) is a common name for various alkaloid arrow poisons originating from plant extracts.
Pralidoxime. Pralidoxime (2-pyridine aldoxime methyl chloride) or 2-PAM, usually as the chloride or iodide salts, belongs to a family of compounds called oximes that bind to organophosphate -inactivated acetylcholinesterase. [ 1 ] It is used to treat organophosphate poisoning [ 2 ] in conjunction with atropine and either diazepam or midazolam ...
The primary antidote to brodifacoum poisoning is immediate administration of vitamin K 1 (dosage for humans: initially slow intravenous injections of 10–25 mg repeated at 3–6 hours until normalisation of the prothrombin time; then 10 mg orally four times daily as a "maintenance dose"). It is an extremely effective antidote, provided the ...
Frequency. ~2,500 cases per year (US)[2] Digoxin toxicity, also known as digoxin poisoning, is a type of poisoningthat occurs in people who take too much of the medication digoxinor eat plants such as foxglovethat contain a similar substance. [1][2]Symptoms are typically vague.[1]
t. e. Benzodiazepine overdose (BZD OD) describes the ingestion of one of the drugs in the benzodiazepine class in quantities greater than are recommended or generally practiced. The most common symptoms of overdose include central nervous system (CNS) depression, impaired balance, ataxia, and slurred speech.
Batrachotoxin (BTX) is an extremely potent cardiotoxic and neurotoxic steroidal alkaloid found in certain species of beetles, birds, and frogs. The name is from the Greek word βάτραχος, bátrachos, 'frog'. [ 3 ] Structurally-related chemical compounds are often referred to collectively as batrachotoxins.