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Allele. An allele[1], or allelomorph, is a variant of the sequence of nucleotides at a particular location, or locus, on a DNA molecule. [2] Alleles can differ at a single position through single nucleotide polymorphisms (SNP), [3] but they can also have insertions and deletions of up to several thousand base pairs. [4]
The genotype of an organism is its complete set of genetic material. [1] Genotype can also be used to refer to the alleles or variants an individual carries in a particular gene or genetic location. [2] The number of alleles an individual can have in a specific gene depends on the number of copies of each chromosome found in that species, also ...
Each line shows one of the three possible genotypes. In population genetics, the Hardy–Weinberg principle, also known as the Hardy–Weinberg equilibrium, model, theorem, or law, states that allele and genotype frequencies in a population will remain constant from generation to generation in the absence of other evolutionary influences.
Allele frequency spectrum. In population genetics, the allele frequency spectrum, sometimes called the site frequency spectrum, is the distribution of the allele frequencies of a given set of loci (often SNPs) in a population or sample. [1][2][3][4] Because an allele frequency spectrum is often a summary of or compared to sequenced samples of ...
Allele frequency. Allele frequency, or gene frequency, is the relative frequency of an allele (variant of a gene) at a particular locus in a population, expressed as a fraction or percentage. [1] Specifically, it is the fraction of all chromosomes in the population that carry that allele over the total population or sample size.
A haplotype (haploid genotype) is a group of alleles in an organism that are inherited together from a single parent. [1][2] Many organisms contain genetic material (DNA) which is inherited from two parents. Normally these organisms have their DNA organized in two sets of pairwise similar chromosomes. The offspring gets one chromosome in each ...
Genotype–phenotype distinction. Similar genotypic changes may result in similar phenotypic alterations, even across a wide range of species. [1] The genotype–phenotype distinction is drawn in genetics. The "genotype" is an organism's full hereditary information. The "phenotype" is an organism's actual observed properties, such as morphology ...
Consider a gene with two alleles, A or B. In diploidy, populations consisting of N individuals have 2N copies of each gene. An individual can have two copies of the same allele or two different alleles. The frequency of one allele is assigned p and the other q.