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In 1832 produced chloral hydrate, the first synthetic sleeping drug. In 1833 French chemist Anselme Payen was the first to discover an enzyme, diastase. In 1834, François Mothes and Joseph Dublanc created a method to produce a single-piece gelatin capsule that was sealed with a drop of gelatin solution.
Sales (USD millions/year) ∆ vs 2014 1 Adalimumab: Humira Biologic Rheumatoid arthritis: AbbVie Inc. 14,012 1,469 2 Ledipasvir/sofosbuvir: Harvoni Small molecule Hepatitis C: Gilead Sciences: 13,864 11,737 3 Etanercept: Enbrel Biologic Rheumatoid arthritis: Amgen. Pfizer. 8,697 4,009 4 Infliximab: Remicade Biologic Crohn's Disease Rheumatoid ...
The WHO Model List of Essential Medicines (aka Essential Medicines List or EML[ 1 ]), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system. [ 2 ] The list is frequently used by countries to help develop their own local lists of ...
Billboard. 200 number-one albums of 2024. Taylor Swift has reigned the chart the longest during 2024, spending a cumulative 17 weeks atop the chart with 1989 (Taylor's Version) (2023) and The Tortured Poets Department (2024). This is a list of the albums ranked number one in the United States during 2024. The top-performing albums and EPs in ...
The following table lists the largest biotechnology and pharmaceutical companies ranked by revenue in billion USD. The change column indicates the company's relative position in this list compared to its relative position in the preceding year; i.e., an increase would be moving closer to rank 1 and vice versa.
Alcohol (from Arabic الكحل (al-kuḥl) 'kohl'), [11] sometimes referred to by the chemical name ethanol, is the second most consumed psychoactive drug globally behind caffeine, [12] and one of the most widely abused drugs in the world. [13] It is a central nervous system (CNS) depressant, decreasing electrical activity of neurons ...
[20] [21] It is on the World Health Organization's List of Essential Medicines. [22] Fentanyl continues to fuel an epidemic of synthetic opioid drug overdose deaths in the United States. From 2011 to 2021, prescription opioid deaths per year remained stable, while synthetic opioid deaths per year increased from 2,600 overdoses to 70,601. [23]
While prohibited drugs are generally viewed as being the most dangerous, the misuse of prescription drugs is linked to more deaths in several countries. [ 12 ] [ 16 ] Cocaine and heroin combined caused fewer deaths than prescriptions drugs in the United Kingdom in 2013, [ 17 ] [ 18 ] and fewer deaths than prescription opiates alone in the ...