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The high mineral content of enamel, which makes this tissue the hardest in the human body, also makes it demineralize in a process that often occurs as dental caries, otherwise known as cavities. [13] Demineralization occurs for several reasons, but the most important cause of tooth decay is the ingestion of fermentable carbohydrates.
Finally, although mineral and elements are in many ways synonymous, minerals are only bioavailable to the extent that they can be absorbed. To be absorbed, minerals either must be soluble or readily extractable by the consuming organism. For example, molybdenum is an essential mineral, but metallic molybdenum has no nutritional benefit.
P11-4 is a self-assembling β-peptide. It builds a 3-D bio-matrix with binding sites for Calcium-ions serving as nucleation point for hydroxyapatite (tooth mineral) formation. The high affinity to tooth mineral is based on matching distances of Ca-ion binding sites on P11-4 and Ca spacing in the crystal lattice of hydroxyapatite.
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