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Examples of translational research are commonly found in education subject association journals and in the MESHGuides which have been designed for this purpose. [5] In bioscience, translational research is a term often used interchangeably with translational medicine or translational science or bench to bedside.
The theory first appeared in an article published by linguist Hans Josef Vermeer in the German Journal Lebende Sprachen, 1978. [2]As a realisation of James Holmes’ map of Translation Studies (1972), [3] [4] skopos theory is the core of the four approaches of German functionalist translation theory [5] that emerged around the late twentieth century.
An example of this is the expression of AMPK in various cancers; its activation triggers a cascade that can ultimately allow the cancer to escape apoptosis (programmed cell death) triggered by nutrition deprivation. Future cancer therapies may involve disrupting the translation machinery of the cell to counter the downstream effects of cancer.
Translational bioinformaticians studying a particular disease would have more sample data regarding a given disease than an individual biologist studying the disease alone. Since the completion of the human genome, new projects are now attempting to systematically analyze all the gene alterations in a disease like cancer rather than focusing on ...
The University of Toronto The Master of Health Science (MHSc) in Translational Research in Health Sciences is a two-year, course-based program is designed for interprofessional students from diverse backgrounds (such as medicine, life sciences, social sciences, engineering, design, and communications) who want to learn creative problem-solving ...
The most widely used definition of knowledge translation was published in 2000 by the Canadian Institutes of Health Research (CIHR): "Knowledge translation (KT) is defined as a dynamic and iterative process that includes synthesis, dissemination, exchange and ethically-sound application of knowledge to improve the health of Canadians, provide more effective health services and products and ...
The focus of translational neuroscience research is to investigate the molecular mechanisms for these disorders, and to investigate the mechanisms of drug delivery to treat these disorders, including an investigation into the impact of the blood-brain barrier on drug delivery, and the role of the body's immune system in neurodegenerative disorders.
A thesis as a collection of articles [1] or series of papers, [2] also known as thesis by published works, [1] or article thesis, [3] is a doctoral dissertation that, as opposed to a coherent monograph, is a collection of research papers with an introductory section consisting of summary chapters. Other less used terms are "sandwich thesis" and ...