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Alfred Russel Wallace was also an advocate of polygenist evolution, claiming that the physical differences in races must have occurred at such a remote time in the past before humans had any intelligence, when natural selection was still operative on human bodies. The differentiation into separate races with distinct physical traits must have ...
Multiregional evolution holds that the human species first arose around two million years ago and subsequent human evolution has been within a single, continuous human species. This species encompasses all archaic human forms such as Homo erectus , Denisovans , and Neanderthals as well as modern forms, and evolved worldwide to the diverse ...
At present the best-understood examples of polygenic adaptation are in humans, and particularly for height, a trait that can be interpreted using data from genome-wide association studies. In a 2012 paper, Joel Hirschhorn and colleagues showed that there was a consistent tendency for the "tall" alleles at genome-wide significant loci to be at ...
The infinitesimal model, also known as the polygenic model, is a widely used statistical model in quantitative genetics and in genome-wide association studies.Originally developed in 1918 by Ronald Fisher, it is based on the idea that variation in a quantitative trait is influenced by an infinitely large number of genes, each of which makes an infinitely small (infinitesimal) contribution to ...
A polygene is a member of a group of non-epistatic genes that interact additively to influence a phenotypic trait, thus contributing to multiple-gene inheritance (polygenic inheritance, multigenic inheritance, quantitative inheritance [1]), a type of non-Mendelian inheritance, as opposed to single-gene inheritance, which is the core notion of ...
According to monogenesis, human language arose only once in a single community, and all current languages come from the first original tongue. On the other hand, according to polygenesis, human languages came into being in several communities independently, and current tongues derived from different sources.
The paradigm of polygenic inheritance as being used to define multifactorial disease has encountered much disagreement. Turnpenny (2004) discusses how simple polygenic inheritance cannot explain some diseases such as the onset of Type I diabetes mellitus, and that in cases such as these, not all genes are thought to make an equal contribution. [12]
Coalescent theory is a model of how alleles sampled from a population may have originated from a common ancestor.In the simplest case, coalescent theory assumes no recombination, no natural selection, and no gene flow or population structure, meaning that each variant is equally likely to have been passed from one generation to the next.