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  2. Denosumab - Wikipedia

    en.wikipedia.org/wiki/Denosumab

    Similarly to bisphosphonates, denosumab appears to be implicated in increasing the risk of osteonecrosis of the jaw (ONJ) following extraction of teeth or oral surgical procedures but, unlike bisphosphonate, the risk declines to zero approximately 6 months after injection. [23] Invasive dental procedures should be avoided during this time.

  3. Intracerebroventricular injection - Wikipedia

    en.wikipedia.org/wiki/Intracerebroventricular...

    These ICV injections result in models for the sporadic Alzheimer's disease (sAD) form, rather than familial. A characteristic of sAD is an insulin-resistant brain state (IRBS). Streptozotocin is a beta-cytotoxic drug and by injecting it directly into the cerebral ventricles, the treated mice develop symptoms that align with sAD symptoms in humans.

  4. Medication-related osteonecrosis of the jaw - Wikipedia

    en.wikipedia.org/wiki/Medication-related_osteo...

    There is no known prevention for bisphosphonate-associated osteonecrosis of the jaw. [6] Avoiding the use of bisphosphonates is not a viable preventive strategy on a general-population basis because the medications are beneficial in the treatment and prevention of osteoporosis (including prevention of bony fractures) and treatment of bone cancers.

  5. Bisphosphonate - Wikipedia

    en.wikipedia.org/wiki/Bisphosphonate

    In large studies, women taking bisphosphonates for osteoporosis have had unusual fractures ("bisphosphonate fractures") in the femur (thigh bone) in the shaft (diaphysis or sub-trochanteric region) of the bone, rather than at the femoral neck, which is the most common site of fracture. However, these fractures are rare (12 in 14,195 women ...

  6. Drug delivery to the brain - Wikipedia

    en.wikipedia.org/wiki/Drug_delivery_to_the_brain

    Drug delivery to the brain is the process of passing therapeutically active molecules across the bloodbrain barrier into the brain. This is a complex process that must take into account the complex anatomy of the brain as well as the restrictions imposed by the special junctions of the bloodbrain barrier.

  7. Prediabetes for Men: Everything You Need to Know, From ...

    www.aol.com/prediabetes-men-everything-know...

    Prediabetes, often considered the step before diabetes, is when you have higher than usual blood glucose (blood sugar) levels. Your levels aren’t high enough to be classified as type 2 diabetes.

  8. The Best Tea for Better Brain Health, According to Dietitians

    www.aol.com/lifestyle/best-tea-better-brain...

    “Green tea’s flavonoids help new brain cells grow, keeping current brain cells healthy and promoting blood flow to the part of the brain that nourishes our emotional regulation center,” says ...

  9. Ragdoll Cat Listed on Clinic Schedule Leaves Vet Tech Totally ...

    www.aol.com/ragdoll-cat-listed-clinic-schedule...

    You'll never find someone who loves Ragdoll cats like one woman does. The vet tech was so excited when she saw there was a Ragdoll on the schedule for that day.