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Contezolid (MRX-I) has reported phase 1 data [12] and phase III data. [13] In 2021, a new drug summary was published by ADIS Press. [14] In June 2021, marketing approval was granted by the Chinese National Medical Products Administration (NMPA) for use of oral contezolid in moderate to severe complicated skin and skin structure infections. [15]
Contezolid (trade name Youxitai) is an antibiotic of the oxazolidinone class. [1] [2] It is effective against Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), Streptococcus pyogenes, Streptococcus agalactiae, and other bacteria.
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The Journal of Political Economy is a monthly peer-reviewed academic journal published by the University of Chicago Press. Established by James Laurence Laughlin in 1892, it covers both theoretical and empirical economics . [ 1 ]
An article in the May issue of the New England Journal of Medicine called for wider U.S. use of medication-assisted therapies for addicts, commonly referred to as MATs. It was written by Dr. Nora Volkow, director of the U.S. National Institute on Drug Abuse — which helped research Suboxone before it earned FDA approval in 2002 — along with ...
MRX may refer to: The ABCG2 gene; MRX complex, DNA damage repair complex in yeast; The Magnetic Reconnection eXperiment led by DoE's Princeton Plasma Physics Laboratory;
DNA end resection is key in determining the correct pathway in NHEJ. For NHEJ pathway to occur, positive regulators such as the Ku and MRX complex mediate recruitment of other NHEJ-associated proteins such as Tel1, Lif1, Dnl4, and Nej1. [3] Since NHEJ does not rely on end resection, NHEJ could only happen in the G1 phase of the cell cycle.
The MRX complex is a heterotrimeric protein complex consisting of Mre11, Rad50, and Xrs2. It is a budding yeast homolog of the mammalian Mre11-Rad50-Nbs1 (MRN) DNA damage repair complex. Double-strand break repair