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Polypharmacy is most commonly defined as the use of five or more medications daily by an individual. [6] However, the definition of polypharmacy is still debated and can vary from two to 11 concurrent medications. [6] Any drug: Cannabis: Amp joint [7] Any drug: Nicotine: Cooler [5] Any β-Carboline containing plant (e.g. Banisteriopsis caapi or ...
Drug Adverse effects Cinchona bark Cinchona pubescens: Warfarin Possible additive effect [3] Chamomile: Blood thinners [23] Devil's Claw: grapple plant, wood spider Harpagophytum: Warfarin Additive effect [3] Ephedra Ephedra: Caffeine, decongestants, stimulants [15] Increases sympathomimetic effect of ephedra [3] Feverfew: featherfew Tanacetum ...
The combination was first introduced as the name Trigesic, as the formula of 125 mg paracetamol, 230 mg aspirin, and 30 mg caffeine, in July 1950 by Squibb, which is now Bristol Myers Squibb, but was recalled in the following year due to several reports that the drug might cause blood dyscrasia. [5]
When two drugs affect each other, it is a drug–drug interaction (DDI). The risk of a DDI increases with the number of drugs used. [1] A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drug–drug interactions. [2] Drug interactions can be of three kinds ...
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If the combination of two drugs in combination therapy has an effect lower than the sum of the effects of the two drugs acting independently, also known as antagonistic effect, the drugs will seldom be prescribed together in the same therapy. Drug or chemical combinations with additive effects can cause adverse effects.
Some state that certain users can become addicted and therefore unable to decrease use even though they know there are negative health effects. [3] [113] Caffeine does not appear to be a reinforcing stimulus, and some degree of aversion may actually occur, with people preferring placebo over caffeine in a study on drug abuse liability published ...
One of the main reasons Ozempic and other GLP-1 agonist medications are so effective is because they target your brain, not just your stomach. While this bodes well for weight loss, some users are ...