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On the flip side, a diet high in added sugar, refined carbs, and saturated fat increases blood sugar and worsens insulin resistance, in turn, leading to type 2 diabetes, adds Palinski-Wade.
[60] [61] The thiazolidinediones, on the other hand, may cause weight gain, but decrease central obesity. [62] Diabetics also achieve modest weight loss with fluoxetine and orlistat over 12–57 weeks. [63] Rimonabant (Acomplia), another drug, had been withdrawn from the market. It worked via a specific blockade of the endocannabinoid system.
Another small study on people without diabetes who were overweight or had obesity found that those taking metformin lost between 5.6 and 6.5 percent of their body weight. In contrast, the control ...
Weight loss is so powerful that research has found that people at high risk for diabetes may reduce their chances of developing diabetes by 58% after losing 5% to 7% of their body weight.
A high protein diet relative to a low-fat or high-carbohydrate diet may increase thermogenesis and decrease appetite leading to weight reduction, [53] particularly 3-6 months into a diet when rapid weight loss is observed. [54] However, these advantages may be reduced later at 12–24 months into a diet during the slow weight loss phase. [54]
A diet high in plant fibre was recommended by James Anderson. [34] This may be understood as continuation of the work of Denis Burkitt and Hugh Trowell on dietary fibre, [35] which may be understood as a continuation of the work of Price. [36] It is still recommended that people with diabetes consume a diet that is high in dietary fiber.
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