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Jostel's TSH index (TSHI or JTI), also referred to as Jostel's thyrotropin index or Thyroid Function index (TFI), is a method for estimating the thyrotropic (i.e. thyroid stimulating) function of the anterior pituitary lobe in a quantitative way. [1] [2] The equation has been derived from the logarithmic standard model of thyroid homeostasis.
The most common isotope used in diagnostic scans is Technetium-99m, used in approximately 85% of all nuclear medicine diagnostic scans worldwide. It is used for diagnoses involving a large range of body parts and diseases such as cancers and neurological problems. [1]
Technetium (99m Tc) tetrofosmin is a drug used in nuclear medicine cardiac imaging. It is sold under the brand name Myoview ( GE Healthcare ). The radioisotope , technetium-99m , is chelated by two 1,2- bis [di-(2-ethoxyethyl)phosphino]ethane ligands which belong to the group of diphosphines and which are referred to as tetrofosmin .
A nuclear medicine parathyroid scan demonstrates a parathyroid adenoma adjacent to the left inferior pole of the thyroid gland. The above study was performed with Technetium-Sestamibi (1st column) and Iodine-123 (2nd column) simultaneous imaging and the subtraction technique (3rd column).
Kits are available that contain the reducing agent, usually tin(II) and ligands. These kits are sterile, pyrogen-free, easily purchased, and can be stored for long periods of time. The reaction with 99m Tc O − 4 takes place directly after elution from the generator column and shortly before its intended use. A high organ specificity is ...
Any thyroid residual along the descent course may lead to the development of ectopic thyroid glands. Thyroid carcinomas, thyroiditis, and goiter may develop within any ectopic thyroid tissue. [1] Thyroid scanning with technetium-99 m (Tc99m) plays an important role in detecting orthotopic and ectopic thyroid tissue.
Thyroid function tests (TFTs) is a collective term for blood tests used to check the function of the thyroid. [1] TFTs may be requested if a patient is thought to suffer from hyperthyroidism (overactive thyroid) or hypothyroidism (underactive thyroid), or to monitor the effectiveness of either thyroid-suppression or hormone replacement therapy.
Technetium (99m Tc) sestamibi is a lipophilic cation which, when injected intravenously into a patient, distributes in the myocardium proportionally to the myocardial blood flow. Single photon emission computed tomography ( SPECT ) imaging of the heart is performed using a gamma camera to detect the gamma rays emitted by the technetium-99m as ...