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  2. AST/ALT ratio - Wikipedia

    en.wikipedia.org/wiki/AST/ALT_ratio

    The proportion of AST to ALT in hepatocytes is about 2.5:1, but because AST is removed from serum by the liver sinusoidal cells twice as quickly (serum half-life t 1/2 = 18 hr) compared to ALT (t 1/2 = 36 hr), so the resulting serum levels of AST and ALT are about equal in healthy individuals, resulting in a normal AST/ALT ratio around 1.

  3. Liver function tests - Wikipedia

    en.wikipedia.org/wiki/Liver_function_tests

    Liver function tests (LFTs or LFs), also referred to as a hepatic panel or liver panel, are groups of blood tests that provide information about the state of a patient's liver. [1] These tests include prothrombin time (PT/INR), activated partial thromboplastin time (aPTT), albumin , bilirubin (direct and indirect), and others.

  4. Elevated transaminases - Wikipedia

    en.wikipedia.org/wiki/Elevated_transaminases

    In medicine, the presence of elevated transaminases, commonly the transaminases alanine transaminase (ALT) and aspartate transaminase (AST), may be an indicator of liver dysfunction. [ 1 ] [ 2 ] Other terms include transaminasemia , [ 3 ] and elevated liver enzymes (though they are not the only enzymes in the liver).

  5. Aspartate transaminase - Wikipedia

    en.wikipedia.org/wiki/Aspartate_transaminase

    Serum AST level, serum ALT (alanine transaminase) level, and their ratio (AST/ALT ratio) are commonly measured clinically as biomarkers for liver health. The tests are part of blood panels. The half-life of total AST in the circulation approximates 17 hours and, on average, 87 hours for mitochondrial AST. [4] Aminotransferase is cleared by ...

  6. Alanine transaminase - Wikipedia

    en.wikipedia.org/wiki/Alanine_transaminase

    ALT is commonly measured clinically as part of liver function tests and is a component of the AST/ALT ratio. [6] When used in diagnostics, it is almost always measured in international units/liter (IU/L) [7] or μkat. While sources vary on specific reference range values for patients, 0-40 IU/L is the standard reference range for experimental ...

  7. Reference ranges for blood tests - Wikipedia

    en.wikipedia.org/wiki/Reference_ranges_for_blood...

    Enzyme activity is commonly used for e.g. liver function tests like AST, ALT, LD and γ-GT in Sweden. [5] Percentages and time-dependent units (mol/s) are used for calculated derived parameters, e.g. for beta cell function in homeostasis model assessment or thyroid's secretory capacity. [citation needed]

  8. Hepatitis - Wikipedia

    en.wikipedia.org/wiki/Hepatitis

    In the early stages (as with NAFLD and early NASH), most patients are asymptomatic or have mild right upper quadrant pain, and diagnosis is suspected on the basis of abnormal liver function tests. [33] As the disease progresses, symptoms typical of chronic hepatitis may develop. [45]

  9. Stauffer syndrome - Wikipedia

    en.wikipedia.org/wiki/Stauffer_syndrome

    The hepatic abnormalities are not due to tumor infiltration of the liver or intrinsic liver disease; they instead reflect the presence of a paraneoplastic syndrome. [1] Stauffer syndrome causes abnormal liver function tests, especially those that reflect the presence of cholestasis, i.e. abnormal bile flow. Hepatosplenomegaly may also be observed.

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