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Hypoxic ventilatory response (HVR) is the increase in ventilation induced by hypoxia that allows the body to take in and transport lower concentrations of oxygen at higher rates. It is initially elevated in lowlanders who travel to high altitude, but reduces significantly over time as people acclimatize .
A controlled F I O 2 is particularly important for patients whose ventilation is dependent on hypoxic drive, [5] as may be seen in patients with chronic obstructive pulmonary disease. Administration of too much oxygen may lead to a reduction in their respiratory rate and retention of carbon dioxide, and ultimately to reduced consciousness or ...
A significant alteration in ventilation that affects elimination of CO 2 can cause a respiratory acid-base disorder. The PaCO 2 is maintained within a range of 35–45 mm Hg in normal states. [citation needed] Alveolar ventilation is under the control of the respiratory center, which is located in the pons and the medulla.
Hypoxic air systems can be integrated with the building management system and can include systems to recover the heat generated by the hypoxic air generator that, would otherwise be wasted. [ 5 ] Air with low oxygen concentration is transported to the protected volumes through dedicated pipes or, more simply, via an existing ventilation system .
Note: ( In cases with an apneic patient the best results will be achieved using the Two person bag-valve-mask technique.) Proper training and considerable practice is required to correctly use the FROPVD devices. [3] The main components of flow-restricted, oxygen-powered ventilation devices include An inspiratory pressure safety release valve.
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While the maintenance of ventilation/perfusion ratio during regional obstruction of airflow is beneficial, HPV can be detrimental during global alveolar hypoxia which occurs with exposure to high altitude, where HPV causes a significant increase in total pulmonary vascular resistance, and pulmonary arterial pressure, potentially leading to ...
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