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The common frog is a poikilotherm and is able to function over a wide range of body core temperatures.. A poikilotherm (/ ˈ p ɔɪ k ə l ə ˌ θ ɜːr m, p ɔɪ ˈ k ɪ l ə ˌ θ ɜːr m /) is an animal (Greek poikilos – 'various', 'spotted', and therme – 'heat') whose internal temperature varies considerably.
The signs and symptoms of ischemia vary, as they can occur anywhere in the body and depend on the degree to which blood flow is interrupted. [4] For example, clinical manifestations of acute limb ischemia (which can be summarized as the "six P's") include pain, pallor, pulseless, paresthesia, paralysis, and poikilothermia.
Acute limb ischaemia (ALI) occurs when there is a sudden lack of blood flow to a limb [1] within 14 days of symptoms onset. [2] On the other hand, when the symptoms exceed 14 days, [3] it is called critical limb ischemia (CLI).
Statement Highlights: A new American Heart Association scientific statement provides an updated roadmap for incorporating patient-reported symptoms and quality of life assessments into routine ...
Critical limb ischemia is diagnosed by the presence of ischemic rest pain, and an ulcers that will not heal or gangrene due to insufficient blood flow. [3] Insufficient blood flow may be confirmed by ankle-brachial index (ABI), ankle pressure, toe-brachial index (TBI), toe systolic pressure, transcutaneous oxygen measurement (TcpO2 ), or skin perfusion pressure (SPP).
Treatment may include physical therapy or, if that fails, surgery. [1] ACS is an emergency, and outcome largely depends on the time to diagnosis and treatment. [12] If treated within 3 hours, the prognosis is favorable. [12] Complications and permanent damage can occur. [13] ACS occurs in about 1-10% of those with a tibial shaft fracture. [6]
Peripheral artery disease (PAD), or limb ischemia, affects the femoral, popliteal, or iliac arteries. [17] PAD is caused by atherosclerotic plaques that occlude blood flow to extremities. [ 5 ] Once blood flow is impeded, ischemic muscle cells switch from aerobic to anaerobic metabolism to cope with oxygen scarcity.
A medical guideline (also called a clinical guideline, standard treatment guideline, or clinical practice guideline) is a document with the aim of guiding decisions and criteria regarding diagnosis, management, and treatment in specific areas of healthcare. Such documents have been in use for thousands of years during the entire history of medicine