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The study, which hasn’t been published yet in a peer-reviewed journal, tracked health data and potential long-term side effects of using metformin during pregnancy for up to 11 years postpartum.
A total review of metformin use during pregnancy compared to insulin alone found good short-term safety for both the mother and baby, but safety in the longer term is unclear. [61] Several observational studies and randomized controlled trials found metformin to be as effective and safe as insulin for the management of gestational diabetes.
They work best with patients over 40 years old who have had diabetes mellitus for under ten years. They cannot be used with type 1 diabetes, or diabetes of pregnancy. They can be safely used with metformin or glitazones. The primary side-effect is hypoglycemia, which appears to happen more commonly with sulfonylureas than with other treatments ...
As noted, timing your metformin dosage is crucial for mitigating the risk — and overall severity — of side effects. But what are those side effects exactly? The most common side effects of ...
One study among 96 patients diagnosed with gestational diabetes in the last three years found that, compared to insulin therapy, metformin had superior effects on blood sugar levels, inflammation ...
Treatment of polycystic ovarian syndrome with metformin during pregnancy has been noted to decrease GDM levels. [94] Almost half of the women did not reach sufficient control with metformin alone and needed supplemental therapy with insulin; compared to those treated with insulin alone, they required less insulin, and they gained less weight. [95]
The dose is usually started low and tapered gradually. Some of the common side effects of the medication is nausea, vomiting and diarrhea. Patients with a family history of medullary thyroid cancer or Multiple Endocrine Neoplasia type 2 should not be prescribed the drug may increase the risk of developing cancer. [37]
Since the fetus is smaller and does not have a fully developed liver, the concentration of alcohol in its bloodstream lasts longer, increasing the chances of detrimental side effects. [69] The severity of effects alcohol may have on a developing fetus depends upon the amount and frequency of alcohol consumed as well as the stage of pregnancy.
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