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The hair follicle is an organ found in mammalian skin. [1] It resides in the dermal layer of the skin and is made up of 20 different cell types, each with distinct functions. The hair follicle regulates hair growth via a complex interaction between hormones, neuropeptides, and immune cells. [1]
A hair follicle is a tube-like structure (pore) that surrounds the root and strand of a hair. Hair follicles exist in the top two layers of your skin. You’re born with over 5 million hair follicles in your body and over one million hair follicles on your head. As you age, hair grows out of your hair follicles.
The placode eventually envelops the dermal condensate, now termed the dermal papilla, forming the hair bulb. The dermal papilla, composed of mesenchymal cells, plays a crucial role in regulating the growth and development of the hair follicle both during embryogenesis and postnatal life.
At the base of the hair, the hair root widens to a round hair bulb. The hair papilla, which supplies the hair root with blood, is found inside the bottom of the hair bulb. New hair cells are constantly being made in the hair bulb, close to the papilla.
The base of the hair follicle includes the dermal papilla and the matrix cell layer. These layers are easily distinguished from one another upon H&E staining. The hair matrix cells are basophilic, which contrasts the pale and lightly eosinophilic areas of the dermal papilla.
The hair follicle is a skin appendage located deep in the dermis of the skin. Its function is to produce hair and enclose the hair shaft . A hair follicle consists of two main layers, an inner (epithelial) root sheath and an outer (fibrous) root sheath.
The hair bulb comprises the expanded portion of the inferior hair follicle and contains the dermal papilla and hair matrix. The dermal papilla consists of mesenchymal cells which function in the regulation of hair growth.
Hair follicles are made up of many different components, but these are the four key structures. The papilla is made up of connective tissue and blood vessels that nourish growing hair. It exists at the very base of a hair follicle.
A hair follicle is a tunnel-shaped structure in the epidermis (outer layer) of the skin. Hair starts growing at the bottom of a hair follicle.
The histology of your hair can vary slightly depending on your ethnicity, being influenced by race and genes. The hair follicles are tubular structures, having a base (hair bulb) that surrounds the hair papilla. It has three inner layers forming the hair shaft. During the growth phase, an extra outer layer (stratum basale) appears.