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What is autosomal dominant inheritance? Autosomal dominant is one way that genetic traits pass from one parent to their child. When a trait is autosomal dominant, only one parent needs to have an altered gene to pass it on.
Autosomal inheritance is a way for genetic conditions to pass from parent to child. It describes genetic variants that sit within one of the autosomes, which are a type of...
Autosomes, or autosomal DNA, make up 22 pairs of chromosomes in your body. Small variations in these genes determine your genetic makeup and whether you inherit certain traits and conditions.
Autosomal dominant or dominance is a pattern of genetic inheritance that occurs within an autosome (non-sex chromosome). The way we look and function is most commonly the result of dominance of one parental gene over the other.
Since autosomal dominant disorders involve autosomes or the non-sex chromosomes, the disorders affect males and females equally. Also, autosomal dominant disorders rarely skip generations because they only require the inheritance of one dominant allele to express the phenotype of the disorder.
Several basic modes of inheritance exist for single-gene disorders: autosomal dominant, autosomal recessive, X-linked dominant, and X-linked recessive. However, not all genetic conditions will follow these patterns, and other rare forms of inheritance such as mitochondrial inheritance exist.
An autosomal pattern of inheritance occurs in families affected with a genetic disease whose gene is not on a sex chromosome. Patients affected with autosomal recessive (AR) diseases have a disease allele on each chromosome.