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Afterload is the mean tension produced by a chamber of the heart in order to contract. It can also be considered as the ‘load’ that the heart must eject blood against. Afterload is, therefore, a consequence of aortic large vessel compliance, wave reflection, and small vessel resistance (LV afterload) or similar pulmonary artery parameters (RV afterload
In oncology, polycythemia vera (PV) is an uncommon myeloproliferative neoplasm in which the bone marrow makes too many red blood cells. [1] The majority of cases [ 2 ] are caused by mutations in the JAK2 gene, most commonly resulting in a single amino acid change in its protein product from valine to phenylalanine at position 617.
A PV diagram plots the change in pressure P with respect to volume V for some process or processes. Typically in thermodynamics, the set of processes forms a cycle, so that upon completion of the cycle there has been no net change in state of the system; i.e. the device returns to the starting pressure and volume.
Myeloproliferative neoplasms (MPNs) are a group of rare blood cancers in which excess red blood cells, white blood cells or platelets are produced in the bone marrow. Myelo refers to the bone marrow, proliferative describes the rapid growth of blood cells and neoplasm describes that growth as abnormal and uncontrolled.
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Activation of the sympathetic nervous system, due to anxiety and/or physiological stress, for example hypovolemia caused by dehydration or bleeding. This activation can cause a release of catecholamines such as epinephrine (adrenaline) which can bind to beta-1 adrenergic receptor (β 1 receptors) on cardiac myocytes, activating a type of ...
percutaneous umbilical blood sample PUD: peptic ulcer disease: PUO: pyrexia of unknown origin: PUVA: psoralen UV A (photochemical ultraviolet light A waves) p.v. per vagina (as noun: vaginal examination with manual examination and speculum inspection) PV polycythemia vera PVC (VPC) premature ventricular contraction: PVD: peripheral vascular ...
The origins of pathophysiology as a distinct field date back to the late 18th century. The first known lectures on the subject were delivered by Professor August Friedrich Hecker [ de ] at the University of Erfurt in 1790, and in 1791, he published the first textbook on pathophysiology, Grundriss der Physiologia pathologica [ 2 ] , spanning 770 ...