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Bempegaldesleukin (development code NKTR-214) is an experimental anti-cancer drug candidate. It is a PEGylated interleukin-2 (IL-2) acting as a CD122-preferential IL-2 pathway agonist designed to activate and proliferate CD8 + T cells and NK cells.
Stable versions of the software are released on a 1-month basis and it is supported by an extensive testing framework [21] which ensures correctness across a range of platforms and architectures. Other capabilities currently under active development include p-adaption, [ 22 ] r-adaption and support for accelerators ( GPGPU , Intel Xeon Phi ).
Nektar Therapeutics is an American biopharmaceutical company. The company was founded in 1990 and is based in San Francisco, California. [2] The company develops new drug candidates by applying its proprietary PEGylation and advanced polymer conjugate technologies to modify chemical structure of substances [3], which improves drug characteristics like retention and solubility. [4]
RECAP [11] is software which allows users to automatically search for free copies of documents during a search in the fee-based online U.S. federal court document database PACER (Public Access to Court Electronic Records), and to help build up a free alternative database. [12]
The system is decentralized with each court running its own servers and its own copy of the software. Each court has a live server and separate training and test servers. The test server is used to make changes and install new versions before "going to live." The training server allows users to learn how to use CM/ECF without affecting live cases.
The Software Updater cannot uninstall updates, although this can be accomplished by other package managers such as Ubuntu Software Center and more technically advanced ones such as Synaptic. In Ubuntu, the Software Updater can update the operating system to new versions which are released every six months for standard releases or every two ...
Pacer (also known as Rubicon-like) is a protein that in humans is encoded by the RUBCNL gene. [5] Pacer has been shown to increase cellular autophagy through regulation of PI3KC3. [6] Pacer contains a Rubicon homology (RH) domain at its C-terminus, which mediates binding to small GTPase Rab7 when Rab7 is phosphorylated following mitochondrial ...
PACER (acronym for Public Access to Court Electronic Records) is an electronic public access service for United States federal court documents. It allows authorized users to obtain case and docket information from the United States district courts , United States courts of appeals , and United States bankruptcy courts .