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Whooping cough (/ ˈ h uː p ɪ ŋ / or / ˈ w uː p ɪ ŋ /), also known as pertussis or the 100-day cough, is a highly contagious, vaccine-preventable bacterial disease. [1] [10] Initial symptoms are usually similar to those of the common cold with a runny nose, fever, and mild cough, but these are followed by two or three months of severe coughing fits. [1]
Cases of whooping cough are surging across the country. Doctors share symptoms, how to prevent pertussis, vaccination information, and treatments amid outbreak.
Bordetella pertussis is a Gram-negative, aerobic, pathogenic, encapsulated coccobacillus bacterium of the genus Bordetella, and the causative agent of pertussis or whooping cough. Its virulence factors include pertussis toxin , adenylate cyclase toxin , filamentous haemagglutinin , pertactin , fimbria , and tracheal cytotoxin .
Fortunately, whooping cough is preventable by a series of vaccines that many people receive as an infant called DTaP - which stands for Diphtheria, Tetanus, and Pertussis.
Two of the most overlooked symptoms of whooping cough are a runny nose and congestion. That's one of the things that makes it so tricky to catch early. "Symptoms may mirror that of the common cold.
Pertussis toxin (PT) is a protein-based AB 5-type exotoxin produced by the bacterium Bordetella pertussis, [2] which causes whooping cough. PT is involved in the colonization of the respiratory tract and the establishment of infection. [ 3 ]
Whooping cough, also known as pertussis, is joining the list of respiratory illnesses that are rising in the U.S. this winter. ... These symptoms can include rapid and uncontrollable coughing fits ...
Whooping cough is often difficult to diagnose because in its early stages, it frequently mimics the common cold, with symptoms including a runny nose, low grade fever and occasional cough. Later ...