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Thyrotoxicosis factitia (alimentary thyrotoxicosis, exogenous thyrotoxicosis) [1] [2] is a condition of thyrotoxicosis caused by the ingestion [3] of exogenous thyroid hormone. [4] [5] It can be the result of mistaken ingestion of excess drugs, such as levothyroxine [6] and triiodothyronine, [7] or as a symptom of Munchausen syndrome.
Thyroglobulin antibodies are specific for thyroglobulin, a 660 kDa matrix protein involved in the process of thyroid hormone production. They are found in 70% of Hashimoto's thyroiditis, 60% of idiopathic hypothyroidism, 30% of Graves' disease, a small proportion of thyroid carcinoma and 3% of normal individuals.
Anti-thyroglobulin antibodies This page was last edited on 27 December 2019, at 18:13 (UTC). Text is available under the Creative Commons ...
Graves' disease is an autoimmune disorder, in which the body produces antibodies that are specific to a self-protein - the receptor for thyroid-stimulating hormone. (Antibodies to thyroglobulin and to the thyroid hormones T3 and T4 may also be produced.) These antibodies cause hyperthyroidism because they bind to the TSHr and chronically ...
[4] [5] It can be distinguished from subacute granulomatous thyroiditis by lack of pain, presence of TPO or thyroglobulin (Tg) antibodies, and normal inflammatory markers. [ 4 ] [ 5 ] Fine needle aspiration (FNA) should be performed in patients who also have a thyroid nodule to rule out thyroid cancer.
Thyroid diseases are highly prevalent worldwide, [10] [11] [12] and treatment varies based on the disorder. Levothyroxine is the mainstay of treatment for people with hypothyroidism, [13] while people with hyperthyroidism caused by Graves' disease can be managed with iodine therapy, antithyroid medication, or surgical removal of the thyroid ...
Negative for 14–3–3 protein; May contain antithyroid antibodies; Magnetic resonance imaging abnormalities consistent with encephalopathy (26% of cases) Single photon emission computed tomography shows focal and global hypoperfusion (75% of cases) Cerebral angiography is normal; Thyroid hormone abnormalities are common (>80% of cases ...
Thyroxine-binding globulin (TBG) is a globulin protein encoded by the SERPINA7 gene in humans. TBG binds thyroid hormones in circulation.It is one of three transport proteins (along with transthyretin and serum albumin) responsible for carrying the thyroid hormones thyroxine (T 4) and triiodothyronine (T 3) in the bloodstream.